If you have been on the hunt for a hearty, satisfying dish that combines the warm comforts of a casserole with bold Tex-Mex flavors, the John Wayne Casserole Recipe is your new best friend. This dish layers savory seasoned ground beef, creamy cheeses, and a flaky biscuit crust, resulting in a meal that’s as filling as it is flavorful. Perfect for family dinners or feeding a crowd, this recipe’s blend of spicy, cheesy, and tangy elements will quickly become a dinner staple you look forward to making over and over.

John Wayne Casserole Recipe - Recipe Image

Ingredients You’ll Need

Getting this dish right is all about using simple, accessible ingredients that each bring their own magic to the table. From the rich, seasoned ground beef that forms the base to the biscuit layer that adds a tender crumb, every component plays a crucial role in balancing taste, texture, and visual appeal.

  • Ground beef (1 lb): The hearty protein foundation for this casserole, providing rich, savory flavor and satisfying texture.
  • Taco seasoning (1 packet): Brings that signature Tex-Mex spice and warmth to the beef, ensuring it’s anything but bland.
  • Water (½ cup for beef, ½ cup for biscuit dough): Helps marry the seasoning with the meat and creates the perfect biscuit dough consistency.
  • Diced tomatoes with green chilies (16 oz can, drained): Adds juicy acidity and just enough heat to lift the entire dish.
  • Onion (1 small, chopped): Provides sweetness and aromatic depth that complements the beef perfectly.
  • Sour cream (1 cup): Offers creaminess and a slight tang that lightens and enriches the cheese layer.
  • Mayonnaise (½ cup): Adds smoothness and helps create a luscious, spreadable topping.
  • Shredded cheddar cheese (1 cup): Delivers sharp, melty goodness that defines the casserole’s cheesy layers.
  • Shredded Monterey Jack cheese (1 cup): A milder, creamy cheese that melts beautifully alongside cheddar.
  • Sliced jalapeños (8 oz can, optional): For those who crave a little extra kick, jalapeños bring spicy heat and texture contrast.
  • Biscuit baking mix (2 cups): Acts as the golden, flaky crust, providing an easy shortcut to biscuit perfection.
  • Salt and pepper: Essential seasoning to bring all layers into harmonious flavor.

How to Make John Wayne Casserole Recipe

Step 1: Preheat and Prepare

Start by preheating your oven to 350°F (175°C) and lightly greasing a 9×13-inch baking dish; this small step ensures your casserole won’t stick and makes cleanup a breeze.

Step 2: Cook the Beef and Onions

In a medium skillet over medium heat, brown the ground beef with chopped onion until the meat is cooked through and the onion is tender. Drain any excess fat to keep the casserole from getting greasy. This step is where all your savory flavors begin coming together.

Step 3: Season the Meat

Add the taco seasoning and ½ cup water to the beef mixture, letting it simmer for 2 to 3 minutes so the flavors meld. Then, stir in the drained diced tomatoes with green chilies before removing the skillet from heat. This ingredient mix introduces that signature vibrant Tex-Mex flavor you’re craving.

Step 4: Prepare the Biscuit Layer

In a separate bowl, mix the biscuit baking mix with ½ cup water until a soft dough forms. Press this dough evenly into the prepared baking dish, creating a sturdy but tender base that will soak up the juicy beef flavors beautifully.

Step 5: Assemble the Layers

Spread the cooked beef mixture evenly over the biscuit crust. In another bowl, mix together sour cream, mayonnaise, and half of both the cheddar and Monterey Jack cheeses; then spread this creamy mixture over the beef. Finally, top with the remaining cheeses and sliced jalapeños if you’re using them for that extra zing.

Step 6: Bake to Perfection

Bake the casserole in your preheated oven for 30 to 35 minutes until the cheese is bubbly, and the edges of the biscuit layer turn a mouthwatering golden brown. Let it cool for 5 to 10 minutes before cutting to allow the layers to set for clean slices.

How to Serve John Wayne Casserole Recipe

John Wayne Casserole Recipe - Recipe Image

Garnishes

Adding fresh toppings like chopped cilantro, diced tomatoes, or sliced green onions enhances both the appearance and flavor of the casserole. A dollop of extra sour cream or a drizzle of salsa can also brighten each bite and add an inviting finishing touch.

Side Dishes

This casserole pairs beautifully with simple sides such as a fresh green salad, Mexican street corn, or even some steamed vegetables to add a touch of lightness to your meal. For a heartier spread, consider serving it alongside warm tortillas or Spanish rice.

Creative Ways to Present

For a fun twist, try serving the casserole in individual ramekins for a personal touch. You can also add layers of black beans or corn inside the casserole before baking to customize it further. Presenting it family-style with bowls of extra jalapeños and cheese lets everyone top their slice just the way they like it.

Make Ahead and Storage

Storing Leftovers

Once cooled, cover leftovers tightly with plastic wrap or transfer to an airtight container and refrigerate for up to 3 days. This way, you can enjoy the flavorful John Wayne Casserole Recipe even after a busy day without any extra cooking fuss.

Freezing

You can freeze the assembled, unbaked casserole for up to 2 months. Wrap it well in foil and plastic wrap to prevent freezer burn. When you’re ready to enjoy, thaw it in the refrigerator overnight before baking as usual.

Reheating

Reheat individual slices in the microwave or warm the entire casserole in a 350°F oven for about 15-20 minutes until heated through. This keeps the cheese melty and the biscuit crust pleasantly soft yet slightly crisp.

FAQs

Can I use ground turkey instead of ground beef in the John Wayne Casserole Recipe?

Absolutely! Ground turkey works well as a leaner alternative and absorbs the spices nicely. Just be sure to cook it thoroughly and drain any excess liquid for the best texture.

Is the biscuit baking mix essential for this recipe?

While biscuit baking mix makes preparation quick and easy, you could use homemade biscuit dough if you prefer. The key is having a soft, flaky crust that contrasts with the hearty beef and creamy cheese layers.

How spicy is this casserole? Can I adjust the heat level?

The recipe has a mild to medium level of spice thanks to the taco seasoning and green chilies. If you prefer less heat, omit the jalapeños and use mild taco seasoning. For more heat, add fresh chopped jalapeños or sprinkle in cayenne pepper.

Can I make the John Wayne Casserole Recipe vegetarian?

You can swap the ground beef for beans like black beans or pinto beans. Add extra veggies such as bell peppers and corn to keep it hearty and flavorful. Adjust seasoning as needed for a delicious vegetarian-friendly version.

What makes the John Wayne Casserole Recipe different from other Tex-Mex casseroles?

Its unique layering with a biscuit crust, creamy sour cream and mayo cheese mixture, and the combination of diced tomatoes with green chilies gives it a distinctive texture and bold yet comforting flavor profile that’s hard to resist.

Final Thoughts

If you are looking for a dish that brings bold Tex-Mex flavors, easy preparation, and cozy comfort all rolled into one, you shouldn’t wait any longer to try the John Wayne Casserole Recipe. It’s the perfect recipe to make your next family dinner or gathering a little more special with minimal effort. Trust me, once you taste this cheesy, spicy, and layered delight, it will quickly become a favorite you’ll want to share again and again.

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John Wayne Casserole Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4 from 63 reviews
  • Author: admin
  • Prep Time: 20 minutes
  • Cook Time: 35 minutes
  • Total Time: 55 minutes
  • Yield: 6–8 servings
  • Category: Main Course
  • Method: Baking
  • Cuisine: Tex-Mex, American
  • Diet: Kid-Friendly

Description

John Wayne Casserole is a hearty Tex-Mex inspired dish combining seasoned ground beef, a biscuit base, and layers of creamy cheese and jalapeños. This baked casserole is perfect for family dinners or casual gatherings, offering a delicious blend of savory, spicy, and creamy flavors all in one easy-to-make recipe.


Ingredients

Scale

Beef Layer

  • 1 lb ground beef
  • 1 small onion, chopped
  • 1 packet taco seasoning
  • ½ cup water
  • 1 (16 oz) can diced tomatoes with green chilies, drained
  • Salt and pepper to taste

Biscuit Layer

  • 2 cups biscuit baking mix (like Bisquick)
  • ½ cup water

Cheese & Cream Layer

  • 1 cup sour cream
  • ½ cup mayonnaise
  • 1 cup shredded cheddar cheese, divided
  • 1 cup shredded Monterey Jack cheese, divided
  • 1 (8 oz) can sliced jalapeños (optional)


Instructions

  1. Preheat and Prepare Dish: Preheat the oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish to prevent sticking.
  2. Cook Ground Beef and Onion: In a skillet over medium heat, cook the ground beef and chopped onion until the beef is fully browned and the onion has softened. Drain any excess fat to reduce grease in the casserole.
  3. Add Seasoning and Tomatoes: Stir in the taco seasoning packet and ½ cup water to the cooked beef mixture. Let it simmer for 2–3 minutes so the flavors meld. Then, fold in the drained diced tomatoes with green chilies. Remove the skillet from heat.
  4. Prepare Biscuit Dough: In a separate bowl, combine the biscuit baking mix with ½ cup water until a soft dough forms. Press this dough evenly into the bottom of the greased baking dish to create the biscuit layer.
  5. Assemble Beef Layer: Spread the seasoned beef mixture evenly over the biscuit dough layer, ensuring full coverage.
  6. Mix and Add Cream Cheese Layer: In another bowl, combine sour cream, mayonnaise, and half of the shredded cheddar and Monterey Jack cheeses. Spread this creamy mixture evenly over the beef layer.
  7. Add Remaining Cheese and Jalapeños: Sprinkle the remaining shredded cheeses on top. If desired, arrange sliced jalapeños evenly over the cheese for an extra spicy kick.
  8. Bake: Place casserole in the preheated oven and bake for 30–35 minutes, or until the cheese is bubbly and the edges of the biscuit layer turn golden brown.
  9. Cool and Serve: Allow the casserole to cool for 5–10 minutes to set before slicing into portions and serving.

Notes

  • This casserole is packed with Tex-Mex flavor and is great for feeding a crowd.
  • You can prepare it ahead of time and refrigerate before baking to save time.
  • For added variety, consider including diced bell peppers or black beans in the beef mixture.
  • Adjust jalapeño quantity or omit to suit your preferred spice level.
  • Leftovers can be stored in the refrigerator for up to 3 days and reheated thoroughly before serving.

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